National Cancer Institute Thesaurus

Last uploaded: February 21, 2019

Preferred Name	Receptor Tyrosine Kinase
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17660
code	C17660
DEFINITION	A class of membrane receptors that contain protein tyrosine kinase activity. This enzymatic activity is integral to the function of the receptor as a signal transducer; the phosphorylation event alters the functional activity of its protein substrate.
FULL_SYN	Receptor-Tyrosine Kinase Transmembrane Receptor Protein Tyrosine Kinase TKR Tyrosine Receptor Kinase Receptor-Type Protein-Tyrosine Kinase Receptor Protein-Tyrosine Kinase Tyrosine Kinase Growth Factor Receptor Tyrosine Kinase Receptor RTK TRK EC 2.7.10.1 EGF Receptor-Tyrosine Kinase Family
label	Receptor Tyrosine Kinase
Legacy_Concept_Name	Receptor_Tyrosine_Kinase
Preferred_Name	Receptor Tyrosine Kinase
prefixIRI	C17660
prefLabel	Receptor Tyrosine Kinase
Semantic_Type	Enzyme Amino Acid, Peptide, or Protein Receptor
UMLS_CUI	C0206364
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18106 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17020

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