National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Gel Electrophoresis

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18091

ALT_DEFINITION

A method of separating large molecules (such as DNA fragments or proteins) from a mixture of similar molecules by electrophoretic filtration through a gelatinous matrix. Subject to an electric field, each molecule in the sample mixture migrates through the matrix at a different rate, depending mainly on electrical charge and size, resulting in spatial separation within the matrix of each molecular species in the sample mixture. Agarose and acrylamide in a cylindrical tube or slab gel are commonly used media for electrophoresis of proteins and nucleic acids.

code

C18091

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C85492

Contributing_Source

CDISC

DEFINITION

Gel electrophoresis is a method of separating large molecules (such as DNA fragments or proteins) from a mixture of similar molecules by electrophoretic filtration through a gelatinous matrix. Subject to an electric field, each molecule in the sample mixture migrates through the matrix at a different rate, depending mainly on electrical charge and size, resulting in spatial separation within the matrix of each molecular species in the sample mixture. Agarose and acrylamide in a cylindrical tube or slab gel are commonly used media for electrophoresis of proteins and nucleic acids.

label

Gel Electrophoresis

Legacy_Concept_Name

Gel_Electrophoresis

Preferred_Name

Gel Electrophoresis

prefixIRI

C18091

prefLabel

Gel Electrophoresis

Semantic_Type

Molecular Biology Research Technique

UMLS_CUI

C0596607

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19770

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16536

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http://purl.obolibrary.org/obo/CHMO_0001021 GenEpiO LOOM