National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Receptor

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18106

ALT_DEFINITION

A molecule inside or on the surface of a cell that binds to a specific substance and causes a specific physiologic effect in the cell.

code

C18106

DEFINITION

A protein located on the cell surface, or in the cytoplasm, that binds to a specific signaling factor, such as a hormone, antigen, or neurotransmitter, causing a conformational and functional change in the receptor molecule. The ligand-bound receptor then alters its interaction with target molecules, which leads to changes in cellular physiology through modification of the activity of one or more signal transduction pathways.

FULL_SYN

Receptor Protein

label

Receptor

Legacy_Concept_Name

Receptor

Preferred_Name

Receptor

prefixIRI

C18106

prefLabel

Receptor

Semantic_Type

Amino Acid, Peptide, or Protein

Receptor

UMLS_CUI

C0597357

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17728

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http://purl.bioontology.org/ontology/STY/T192 Semantic Types Ontology LOOM
http://purl.bioontology.org/ontology/LNC/LP21071-3 Logical Observation Identifier Names and Codes LOOM