loading...| Preferred Name |
G Protein-Coupled Receptor |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18239 |
| code |
C18239 |
| DEFINITION |
Cell surface receptors that are coupled to G-proteins (GTP-binding protein). G-protein coupled receptors are thought to have seven membrane spanning domains and have been divided into 2 subclasses: those in which the binding site is in the extracellular domain for example receptors for glycoprotein hormones, such as thyroid stimulating hormone (TSH) and follicle-stimulating hormone (FSH) and those in which the ligand binding site is likely to be in the plane of the 7 transmembrane domains for example rhodopsin and receptors for small neurotransmitters and hormones for example muscarinic acetylcholine receptor. |
| FULL_SYN |
G-Protein Coupled Receptor G Protein-Complex Receptor GPCR G Protein Coupled Receptor G Protein-Complex Receptors |
| label |
G Protein-Coupled Receptor |
| Legacy_Concept_Name |
G_Protein-Coupled_Receptor |
| Preferred_Name |
G Protein-Coupled Receptor |
| prefixIRI |
C18239 |
| prefLabel |
G Protein-Coupled Receptor |
| Semantic_Type |
Amino Acid, Peptide, or Protein Receptor |
| UMLS_CUI |
C0682972 |
| subClassOf |