National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Ephrin Receptor

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18606

code

C18606

DEFINITION

Eph receptor tyrosine kinases and their ligands, the ephrins, appear to lie functionally at the interface between pattern formation and morphogenesis. They play a major role in axonal pathfinding and target recognition during central nervous system (CNS) development. (from Development 1999;126:2033-2044 and Exp Neurol 1999;156:218-22)

DesignNote

The signaling pathways downstream of ephrin receptors are referred to as forward signaling while the signaling pathways downstream of the ephrin ligands are referred to as reverse signaling. (UniProt)

FULL_SYN

EPH

label

Ephrin Receptor

Legacy_Concept_Name

Ephrin_Receptor

Preferred_Name

Ephrin Receptor

prefixIRI

C18606

prefLabel

Ephrin Receptor

Semantic_Type

Enzyme

Amino Acid, Peptide, or Protein

Receptor

UMLS_CUI

C0908506

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20130

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http://purl.obolibrary.org/obo/PR_000025845 International Classification of Diseases Ontology LOOM
http://purl.obolibrary.org/obo/PR_000025845 Protein Ontology LOOM