National Cancer Institute Thesaurus

Last uploaded: February 21, 2019

Preferred Name	Protein Hormone Receptor
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18968
code	C18968
DEFINITION	Typically associated with the cell membrane, Protein Hormone Receptors selectively bind with high affinity to genetically-encoded polymerized amino acids in peptide linkage that have regulatory effects on the activity of specific target cells. A ligand-induced conformational and functional change in the receptor alters its interaction with target molecules, leading to changes in cellular physiology through modification of the activity of signal transduction pathways.
label	Protein Hormone Receptor
Legacy_Concept_Name	Protein_Hormone_Receptor
Preferred_Name	Protein Hormone Receptor
prefixIRI	C18968
prefLabel	Protein Hormone Receptor
Semantic_Type	Amino Acid, Peptide, or Protein Receptor
UMLS_CUI	C1335534
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18106

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