TNF Receptor Family Protein

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19285

C19285

Members of the tumor necrosis factor receptor (TNFR) family play a key role in regulating the immune response to infection. They are cell-surface proteins that interact with a corresponding TNF-related ligand family. The receptors share homology in the extracellular domain, which contains 3 to 6 cysteine-rich pseudorepeats, but are generally not related in their cytoplasmic regions. However, the intracellular domains (ICDs) of TNFR family members TNFR1 and FAS/APO1/CD95, which can activate apoptotic cell death, do have a region of homology in an oligomerization interface known as the death domain. (from OMIM 603366)

Tumor Necrosis Factor Receptor Family

Tumor Necrosis Factor Receptor Superfamily

Tumor Necrosis Factor Receptor

TNF Receptor

TNFR

TNFRSF Protein

TNF Receptor Superfamily

TNF Receptor Family Protein

TNF_Receptor_Family_Protein

TNF Receptor Family Protein

C19285

TNF Receptor Family Protein

Amino Acid, Peptide, or Protein

Receptor

C0077503

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17667