National Cancer Institute Thesaurus

Last uploaded: February 21, 2019

Preferred Name	Immunoglobulin Gene Rearrangement
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20045
code	C20045
DEFINITION	Any process of gene rearrangement that creates a novel junction among the immunoglobuling-coding variable, diversity, joining or constant segments. This process involves sequence recognition, cleavage, excision and ligation by recombinases to create a contiguous protein-coding gene. Immunoglobulin gene rearrangement is involved in generation of antibody diversity.
label	Immunoglobulin Gene Rearrangement
Legacy_Concept_Name	Immunoglobulin_Gene_Rearrangement
Preferred_Name	Immunoglobulin Gene Rearrangement
prefixIRI	C20045
prefLabel	Immunoglobulin Gene Rearrangement
Semantic_Type	Genetic Function
UMLS_CUI	C0017289
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16611

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