National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Neurotrophic Factor

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20391

code

C20391

DEFINITION

A family of protein growth factors produced by the nervous system and peripheral target tissues. These proteins are critical for development, growth, regeneration, survival, and differentiation of neurons.

DesignNote

Neurotrophin signaling is mediated by the Trk family of receptor tyrosine kinases. (IP, N. Y. (1998), The Neurotrophins and Neuropoietic Cytokines: Two Families of Growth Factors Acting on Neural and Hematopoietic Cells. Annals of the New York Academy of Sciences, 840: 97-106. doi: 10.1111/j.1749-6632.1998.tb09553.x)

FULL_SYN

Neurotrophin

label

Neurotrophic Factor

Legacy_Concept_Name

Neurotrophic_Factor

Preferred_Name

Neurotrophic Factor

prefixIRI

C20391

prefLabel

Neurotrophic Factor

Semantic_Type

Biologically Active Substance

Amino Acid, Peptide, or Protein

UMLS_CUI

C0132298

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20424

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