National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Brain-Derived Neurotrophic Factor

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20445

code

C20445

DEFINITION

Brain-derived neurotrophic factor (247 aa, ~28 kDa) is encoded by the human BDNF gene. This protein plays a role in both the development of the nervous system and neuronal survival.

DesignNote

The active form of brain-derived neurotrophic factor is produced by proteolytic cleaves that remove 128 N-terminal residues from the full length precursor protein. (UniProt)

FULL_SYN

Abrineurin

BDNF

label

Brain-Derived Neurotrophic Factor

Legacy_Concept_Name

Brain-Derived_Neurotrophic_Factor

OMIM_Number

113505

Preferred_Name

Brain-Derived Neurotrophic Factor

prefixIRI

C20445

prefLabel

Brain-Derived Neurotrophic Factor

Semantic_Type

Amino Acid, Peptide, or Protein

Swiss_Prot

P23560

UMLS_CUI

C0107103

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20391

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http://purl.bioontology.org/ontology/MESH/D019208 Medical Subject Headings LOOM
http://purl.bioontology.org/ontology/OMIM/113505 Online Mendelian Inheritance in Man LOOM
http://purl.obolibrary.org/obo/PR_000004716 Protein Ontology LOOM