National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Transforming Growth Factor-Beta Superfamily

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20455

code

C20455

DEFINITION

A family of structurally-related cytokines that bind to their cognate serine/threonine kinase receptors as homodimers or heterodimers linked by a single disulfide bond. These proteins play a role in embryonic development, hematopoiesis, tissue repair and extracellular matrix remodeling.

FULL_SYN

Bone-Derived Transforming Growth Factor

Milk Growth Factor

TGF-Beta

TGF B

Transforming Growth Factor-Beta

label

Transforming Growth Factor-Beta Superfamily

Legacy_Concept_Name

Transforming_Growth_Factor-Beta

Preferred_Name

Transforming Growth Factor-Beta Superfamily

prefixIRI

C20455

prefLabel

Transforming Growth Factor-Beta Superfamily

Semantic_Type

Biologically Active Substance

Amino Acid, Peptide, or Protein

UMLS_CUI

C0040690

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20424

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