National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Cytokine

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20464

ALT_DEFINITION

A substance that is made by cells of the immune system. Some cytokines can boost the immune response and others can suppress it. Cytokines can also be made in the laboratory by recombinant DNA technology and used in the treatment of various diseases, including cancer.

code

C20464

DEFINITION

A class of soluble glycoproteins which act nonenzymatically through specific receptors to regulate immune responses. Cytokines are derived from both immune and non-immune cells and are intercellular mediators that differ from hormones in that they are produced by a number of tissue or cell types rather than by specialized glands.

FULL_SYN

Cytokines

label

Cytokine

Legacy_Concept_Name

Cytokine

Preferred_Name

Cytokine

prefixIRI

C20464

prefLabel

Cytokine

Semantic_Type

Immunologic Factor

Amino Acid, Peptide, or Protein

UMLS_CUI

C0079189

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20027

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http://purl.obolibrary.org/obo/FMA_84050 Foundational Model of Anatomy LOOM