Alpha Chemokine

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20467

C20467

Members of the Alpha-Chemokines are referred to also as the 4q chemokine family because the genes encoding members of this family map to human chromosome 4q12-21. The first two cysteine residues of members of this family are separated by a single amino acids and these proteins, therefore, are called also CXC-Chemokines. Some members of the subgroup of the human CXC-Chemokines are defined by the conserved ELR sequence motif (glutamic acid-leucine-arginine) immediately preceding the first cysteine residue near the amino-terminal end. Chemokines with an ELR sequence motif have been found to chemoattract and activate primarily neutrophils. Chemokines without the ELR sequence motif appear to chemoattract and activate monocytes, dendritic cells, T-cells, NK-cells, B-lymphocytes, basophils, and eosinophils.

Chemokine, CXC

CXC Chemokine

4q Chemokine

C-X-C Chemokine

Alpha Chemokine

Alpha_Chemokine

Alpha Chemokine

C20467

Alpha Chemokine

Immunologic Factor

Amino Acid, Peptide, or Protein

C0282553

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20466