loading...| Preferred Name |
Tumor Necrosis Factor |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20535 |
| code |
C20535 |
| DEFINITION |
Tumor necrosis factor (233 aa, ~26 kDa) is encoded by the human TNF gene. This protein is involved in the induction of cytokine expression, the stimulation of cell proliferation and the positive regulation of cell differentiation. |
| DesignNote |
Tumor necrosis factor (TNF) is a serum glycoprotein produced by activated macrophages and other mammalian mononuclear leukocytes which has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. |
| FULL_SYN |
Tumor Necrosis Factor Alpha Tumor Necrosis Factor-alpha (macrophage-derived) TNF-Alpha TNF-A TNF TNFA TNF Alpha Tumor Necrosis Factor Ligand Superfamily Member 2 Tumor Necrosis Factor-Alpha |
| label |
Tumor Necrosis Factor |
| Legacy_Concept_Name |
Tumor_Necrosis_Factor-Alpha |
| OMIM_Number |
191160 |
| Preferred_Name |
Tumor Necrosis Factor |
| prefixIRI |
C20535 |
| prefLabel |
Tumor Necrosis Factor |
| Semantic_Type |
Immunologic Factor Amino Acid, Peptide, or Protein |
| Swiss_Prot |
P01375 |
| UMLS_CUI |
C1456820 |
| subClassOf |