National Cancer Institute Thesaurus

Last uploaded: February 21, 2019

Preferred Name	Transcription Repressor/Corepressor Gene
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20703
code	C20703
DEFINITION	RNA polymerase II transcription of Class II genes involves the TFIID transcription complex comprised of general factors, including TBP, TFIIA, TFIIB, TFIIE, TFIIF, TFIIG/J, and TFIIH, as well as gene-specific factors that include TAFs, which interact with regulatory protein activation domains to enhance transcription. Transcription Corepressor Genes encode a group of transcriptional repressor/co-repressor factors that suppress transcription by binding to the operator. (NCI)
FULL_SYN	Transcription Corepressor Gene
Gene_Encodes_Product	Transcription Repressor/Corepressor
label	Transcription Repressor/Corepressor Gene
Legacy_Concept_Name	Transcription_Corepressor_Gene
Preferred_Name	Transcription Repressor/Corepressor Gene
prefixIRI	C20703
prefLabel	Transcription Repressor/Corepressor Gene
Semantic_Type	Gene or Genome
UMLS_CUI	C1336779
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20710

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