National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Receptor Tyrosine Kinase Gene

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20719

code

C20719

DEFINITION

Tyrosine kinase receptors (TRKs) are a family of genes encoding neurotrophin receptors that include trkA, trkB, and trkC, which are related to development, differentiation, and survival of neural crest-derived neurons and central cholinergic neurons in normal tissue. The genes encoding trkA, trkB, and trkC are designated NTRK1, NTRK2, and NTRK3 and map to chromosomes 1, 9, and 15, respectively. A member of the TRK gene family, trkE, encodes a non-neuronal receptor for nerve growth factor. (from OMIM 600408)

Gene_Encodes_Product

Receptor Tyrosine Kinase

label

Receptor Tyrosine Kinase Gene

Legacy_Concept_Name

Receptor_Tyrosine_Kinase_Gene

Preferred_Name

Receptor Tyrosine Kinase Gene

prefixIRI

C20719

prefLabel

Receptor Tyrosine Kinase Gene

Semantic_Type

Gene or Genome

UMLS_CUI

C1335675

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20103

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25872

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