National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Recombinant Corticotropin

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C212

CAS_Registry

9002-60-2

CHEBI_ID

CHEBI:3892

code

C212

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A recombinant peptide hormone chemically identical to or similar to human polypeptide hormone corticotropin (adrenocorticotropic hormone; ACTH). Secreted by the anterior pituitary gland, circulating ACTH stimulates the adrenal cortex to secrete adrenocortical steroids, especially cortisone, which elevate blood pressure in response to stress. With normally functioning adrenal glands, recombinant corticotropin could be used to achieve pharmacologic effects similar to those from cortisone administration.

FDA_UNII_Code

K0U68Q2TXA

FULL_SYN

Adrenocorticotropic Hormone

CORTICOTROPIN

Adrenocorticotropin

Acthar

ACTH

Therapeutic ACTH

label

Recombinant Corticotropin

Legacy_Concept_Name

Therapeutic_Corticotropin

NSC_Code

25934

25933

16894

PDQ_Closed_Trial_Search_ID

39133

PDQ_Open_Trial_Search_ID

39133

Preferred_Name

Recombinant Corticotropin

prefixIRI

C212

prefLabel

Recombinant Corticotropin

Semantic_Type

Chemical Viewed Functionally

Amino Acid, Peptide, or Protein

UMLS_CUI

C1523997

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2348

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