loading...| Preferred Name |
Niacinamide |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2327 |
| Accepted_Therapeutic_Use_For |
Pellegra, treatment and prophylaxis; Various dermatologic conditions |
| ALT_DEFINITION |
A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Niacinamide helps some enzymes make energy in the cell. It is found in many plant and animal products. It is water-soluble (can dissolve in water) and must be taken in daily. It is being studied to increase the effect of radiation therapy on tumor cells. |
| CAS_Registry |
98-92-0 |
| CHEBI_ID |
CHEBI:17154 |
| Chemical_Formula |
C6H6N2O |
| code |
C2327 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP FDA |
| DEFINITION |
The active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy. |
| Display_Name |
Niacinamide |
| FDA_UNII_Code |
25X51I8RD4 |
| FULL_SYN |
Nicotylamide Nicotinamidum Vitamin PP Nicosedine Nicotinamide 3-Pyridinecarboxamide Nicotinic Acid Amide Pellagra-Preventing Factor Nicamid |
| label |
Niacinamide |
| Legacy_Concept_Name |
Niacinamide |
| NSC_Code |
27452 13128 |
| PDQ_Closed_Trial_Search_ID |
42044 |
| PDQ_Open_Trial_Search_ID |
42044 |
| Preferred_Name |
Niacinamide |
| prefixIRI |
C2327 |
| prefLabel |
Niacinamide |
| Semantic_Type |
Organic Chemical Vitamin |
| UMLS_CUI |
C0028027 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/MESH/D009536 | Medical Subject Headings | LOOM |