loading...| Preferred Name |
ACE Inhibitor |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C247 |
| Accepted_Therapeutic_Use_For |
Hypertension |
| ALT_DEFINITION |
A drug that is used to lower blood pressure. An ACE inhibitor is a type of antihypertensive agent. A pharmaceutical agent that inhibits angiotensin-converting enzyme (ACE), which catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. It is primarily used for the reduction of proteinuria and the treatment of hypertension. |
| CHEBI_ID |
CHEBI:35457 |
| code |
C247 |
| Concept_In_Subset | |
| Contributing_Source |
NICHD |
| DEFINITION |
Any substance that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. |
| FULL_SYN |
Angiotensin-Converting Enzyme Inhibitor |
| Has_NICHD_Parent | |
| label |
ACE Inhibitor |
| Legacy_Concept_Name |
ACE_Inhibitor |
| NICHD_Hierarchy_Term |
ACE Inhibitor |
| Preferred_Name |
ACE Inhibitor |
| prefixIRI |
C247 |
| prefLabel |
ACE Inhibitor |
| Semantic_Type |
Chemical Viewed Functionally |
| UMLS_CUI |
C0003015 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/LNC/LP213629-1 | Logical Observation Identifier Names and Codes | LOOM |