National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Ubiquitin Ligase Gene

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26066

code

C26066

DEFINITION

Ubiquitin Ligase Genes encode eukaryotic enzymes (Ubiquitin Ligases) involved in de/ubiquitination of cellular proteins with ubiquitin through its C-terminus. Regulating the half-lives of many proteins by targeting them for degradation, ubiquitination is associated with many regulated events including protein degradation, chromatin remodeling, heat shock, cell cycle progression, differentiation, antigen presentation, retrovirus assembly, apoptosis, signal transduction, transcriptional activation, biological clocks, receptor down regulation, and endocytosis. (NCI)

FULL_SYN

Ubiquitin Ligase Component Gene

label

Ubiquitin Ligase Gene

Legacy_Concept_Name

Ubiquitin_Ligase_Gene

Preferred_Name

Ubiquitin Ligase Gene

prefixIRI

C26066

prefLabel

Ubiquitin Ligase Gene

Semantic_Type

Gene or Genome

UMLS_CUI

C1336849

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25943

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
There are currently no mappings for this class.