National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
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Preferred Name

Heparin Binding
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26124
code

C26124
DEFINITION

Heparin Binding involves a biophysical interaction between a biological molecule, such as a protein, and heparin, a sulfated glycosaminoglycan of mixed polysaccharide nature, varying in molecular weight, and released by mast cells and basophils in many tissues. Lipotrophic by activation of lipoprotein lipase, anticoagulant heparin also binds to and enhances antithrombin III activity and inhibits several coagulation factors.
label

Heparin Binding
Legacy_Concept_Name

Heparin_Binding
Preferred_Name

Heparin Binding
prefixIRI

C26124
prefLabel

Heparin Binding
Semantic_Type

Molecular Function
UMLS_CUI

C1148608
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18963
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http://purl.obolibrary.org/obo/GO_0008201 Cell Ontology LOOM
http://purl.obolibrary.org/obo/GO_0008201 Gene Ontology LOOM