National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
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Preferred Name

Endothelin-2
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26151
code

C26151
DEFINITION

Endothelin-2, encoded by the human EDN2 gene, is a macrophage chemoattractant. Endothelins are endothelium-derived vasoconstrictor peptides. The expression of this secreted protein by tumors may modulate the behavior of macrophages such that activated cells accumulate in areas of hypoxia. (From LocusLink, Swiss-Prot and NCI)
FULL_SYN

EDN2

Endothelin 2
label

Endothelin-2
Legacy_Concept_Name

Endothelin-2
OMIM_Number

131241
Preferred_Name

Endothelin-2
prefixIRI

C26151
prefLabel

Endothelin-2
Semantic_Type

Amino Acid, Peptide, or Protein
Swiss_Prot

P20800
UMLS_CUI

C0079282
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18515
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http://purl.bioontology.org/ontology/MESH/D019333 Medical Subject Headings LOOM
http://purl.obolibrary.org/obo/CHEBI_80242 Chemical Entities of Biological Interest Ontology LOOM
http://purl.bioontology.org/ontology/OMIM/131241 Online Mendelian Inheritance in Man LOOM
http://purl.obolibrary.org/obo/PR_000006898 Protein Ontology LOOM