Preferred Name |
Interleukin-2 Receptor Subunit Beta |
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26267 |
code |
C26267 |
DEFINITION |
Interleukin-2 receptor subunit beta (551 aa, ~61 kDa) is encoded by the human IL2RB gene. This protein is involved in signal transduction-mediated by and receptor mediated endocytosis of interleukin-2. |
DesignNote |
This protein is the beta subunit of the interleukin 2 receptor and is a type I membrane protein. It is involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. It plays a role in the T cell mediated immune response and is a member of the cytokine receptor family. |
FULL_SYN |
Medium Affinity Interleukin 2 Receptor Subunit Beta Intermediate Affinity Interleukin 2 Receptor Subunit Beta CD122 p75 IL-2 Receptor Subunit Beta P70-75 Interleukin 2 Receptor Beta High Affinity IL-2 Receptor Subunit Beta Medium Affinity Interleukin 2 Receptor Beta Subunit IL2RB High Affinity IL-2 Receptor Beta Subunit Intermediate Affinity Interleukin 2 Receptor Beta Subunit IL2 Receptor Beta IL-2RB CD122 Antigen IL-2R Subunit Beta Interleukin-2 Receptor Beta Chain |
label |
Interleukin-2 Receptor Subunit Beta |
Legacy_Concept_Name |
Interleukin-2_Receptor_Beta |
OMIM_Number |
146710 |
Preferred_Name |
Interleukin-2 Receptor Subunit Beta |
prefixIRI |
C26267 |
prefLabel |
Interleukin-2 Receptor Subunit Beta |
Semantic_Type |
Amino Acid, Peptide, or Protein Receptor |
Swiss_Prot |
P14784 |
UMLS_CUI |
C1173313 |
subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://purl.obolibrary.org/obo/PR_000001381 | Cell Ontology | LOOM | |
http://purl.obolibrary.org/obo/PR_000001381 | Protein Ontology | LOOM |