Preferred Name |
Killer Cell Lectin-Like Receptor Subfamily B Member 1 |
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26477 |
code |
C26477 |
DEFINITION |
Killer cell lectin-like receptor subfamily B member 1 (225 aa, ~25 kDa) is encoded by the human KLRB1 gene. This protein plays a role in the modulation of natural killer cell cytotoxicity. |
DesignNote |
Encoded by human KLRB1 Gene (C-Type Lectin Superfamily, NKRP1 Family) and preferentially expressed by natural killer lymphocytes and some peripheral T-cells, the type II membrane NKRP1A Protein (external C-terminus) contains a 158-amino acid extracellular domain with C-type lectin motifs, a 29-amino acid transmembrane domain, and a 38-amino acid cytoplasmic domain. C-type lectins, including NKRP1 glycoproteins, may regulate NK cell function. NKRP1A protein is 46% identical to rat and mouse NKRP1, and 26% identical to human NKG2A. (from LocusLink, OMIM, and NCI) |
FULL_SYN |
Natural Killer Cell Surface Protein P1A KLRB1 NKR-P1 CD161 Killer Cell Lectin-Like Receptor Subfamily B, Member 1 Protein NKR-P1A NKRP1A Protein CD161 Antigen NKR C-Type Lectin Domain Family 5 Member B Killer Cell Lectin-Like Receptor Subfamily B, Member 1 hNKR-P1A |
label |
Killer Cell Lectin-Like Receptor Subfamily B Member 1 |
Legacy_Concept_Name |
NKRP1A_Protein |
OMIM_Number |
602890 |
Preferred_Name |
Killer Cell Lectin-Like Receptor Subfamily B Member 1 |
prefixIRI |
C26477 |
prefLabel |
Killer Cell Lectin-Like Receptor Subfamily B Member 1 |
Semantic_Type |
Immunologic Factor Amino Acid, Peptide, or Protein |
Swiss_Prot |
Q12918 |
UMLS_CUI |
C0132638 |
subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://purl.bioontology.org/ontology/OMIM/602890 | Online Mendelian Inheritance in Man | LOOM | |
http://purl.obolibrary.org/obo/PR_000025670 | Cell Ontology | LOOM | |
http://purl.obolibrary.org/obo/PR_000025670 | Protein Ontology | LOOM |