loading...| Preferred Name |
MAX-Interacting Protein 1 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28556 |
| code |
C28556 |
| DEFINITION |
Max-interacting protein 1 (228 aa, ~26 kDa) is encoded by the human MXI1 gene. This protein plays a role in transcription factor binding and transcriptional repression. |
| DesignNote |
MAX Interacting Protein 1, encoded by the MXI1 gene, is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. |
| FULL_SYN |
MXI1 MAX Interacting Protein 1 Max Interactor 1 Class C Basic Helix-Loop-Helix Protein 11 MAX Dimerization Protein 2 bHLHc11 MAD2 |
| label |
MAX-Interacting Protein 1 |
| Legacy_Concept_Name |
MAX_Interacting_Protein-1 |
| OMIM_Number |
600020 |
| Preferred_Name |
MAX-Interacting Protein 1 |
| prefixIRI |
C28556 |
| prefLabel |
MAX-Interacting Protein 1 |
| Semantic_Type |
Amino Acid, Peptide, or Protein |
| Swiss_Prot |
P50539 |
| UMLS_CUI |
C0212908 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/PR_000010793 | Protein Ontology | LOOM | |
| http://purl.bioontology.org/ontology/OMIM/600020 | Online Mendelian Inheritance in Man | LOOM |