National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Nitrofurantoin

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29293

CAS_Registry

67-20-9

CHEBI_ID

CHEBI:71415

Chemical_Formula

C8H6N4O5

code

C29293

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic derivative of imidazolidinedione, Nitrofurantoin inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoin is used prophylactically as a urinary anti-infective agent against most gram-positive and gram-negative organisms and for long-term suppression of infections. (NCI04)

FDA_UNII_Code

927AH8112L

FULL_SYN

Macrobid

Macrodantin

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66241

label

Nitrofurantoin

Legacy_Concept_Name

Nitrofurantoin

NSC_Code

44150

2107

Preferred_Name

Nitrofurantoin

prefixIRI

C29293

prefLabel

Nitrofurantoin

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0028156

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C255

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http://purl.bioontology.org/ontology/MESH/D009582 Medical Subject Headings LOOM
http://purl.bioontology.org/ontology/LNC/LP16140-3 Logical Observation Identifier Names and Codes LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 Chemical Entities of Biological Interest Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 GenEpiO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU008460 Logical Observation Identifier Names and Codes LOOM
http://purl.bmicc.cn/ontology/ICD11CN/XM09K7 International Classification of Diseases, 11th Edition, China LOOM