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loading...| Preferred Name |
Sulfonamide Anti-Infective Agent |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29739 |
| ALT_DEFINITION |
A type of antibiotic used to treat infection. |
| code |
C29739 |
| DEFINITION |
A class of natural or synthetic sulfanilamide derivatives with antibacterial activity. Sulfonamides are structural analogs of para-aminobenzoic acid (essential for microbial folate synthesis). Sulfonamides inhibit bacterial metabolism by competing with PABA for dihydropteroate synthase, thereby resulting in disruption of folic acid metabolism and ultimately DNA synthesis. |
| FULL_SYN |
sulfa drug sulfonamide Sulfonamides |
| label |
Sulfonamide Anti-Infective Agent |
| Legacy_Concept_Name |
Sulfonamide_Anti-infective_Agent |
| Preferred_Name |
Sulfonamide Anti-Infective Agent |
| prefixIRI |
C29739 |
| prefLabel |
Sulfonamide Anti-Infective Agent |
| Semantic_Type |
Chemical Viewed Functionally |
| UMLS_CUI |
C0038760 |
| subClassOf |
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