Preferred Name |
Graves Disease |
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3071 |
ALT_DEFINITION |
Hyperthyroidism associated with a diffuse hyperplastic goiter resulting from production of an antibody directed against the thyroid-stimulating hormone (TSH) receptor, which acts as an agonist of TSH. (Braverman, The Thyroid, 6th ed, p648) An autoimmune disorder characterized by excessive immunoglobulin stimulation of the thyroid gland resulting in hyperthyroidism. |
code |
C3071 |
Concept_In_Subset | |
Contributing_Source |
NICHD MedDRA |
DEFINITION |
Hyperthyroidism associated with diffuse hyperplasia of the thyroid gland (goiter), resulting from production of antibodies that are directed against the thyrotropin receptor complex of the follicular epithelial cells. As a result, the thyroid gland enlarges and secrets increased amounts of thyroid hormones. |
FULL_SYN |
Graves' Disease |
Has_NICHD_Parent | |
label |
Graves Disease |
Legacy_Concept_Name |
Graves_Disease |
NICHD_Hierarchy_Term |
Graves Disease |
Preferred_Name |
Graves Disease |
prefixIRI |
C3071 |
prefLabel |
Graves Disease |
Semantic_Type |
Disease or Syndrome |
UMLS_CUI |
C0018213 |
subClassOf |