National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Graves Disease

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3071

ALT_DEFINITION

Hyperthyroidism associated with a diffuse hyperplastic goiter resulting from production of an antibody directed against the thyroid-stimulating hormone (TSH) receptor, which acts as an agonist of TSH. (Braverman, The Thyroid, 6th ed, p648)

An autoimmune disorder characterized by excessive immunoglobulin stimulation of the thyroid gland resulting in hyperthyroidism.

code

C3071

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

Contributing_Source

NICHD

MedDRA

DEFINITION

Hyperthyroidism associated with diffuse hyperplasia of the thyroid gland (goiter), resulting from production of antibodies that are directed against the thyrotropin receptor complex of the follicular epithelial cells. As a result, the thyroid gland enlarges and secrets increased amounts of thyroid hormones.

FULL_SYN

Graves' Disease

Has_NICHD_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3009

label

Graves Disease

Legacy_Concept_Name

Graves_Disease

NICHD_Hierarchy_Term

Graves Disease

Preferred_Name

Graves Disease

prefixIRI

C3071

prefLabel

Graves Disease

Semantic_Type

Disease or Syndrome

UMLS_CUI

C0018213

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3123

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26785

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http://purl.obolibrary.org/obo/HP_0100647 Human Phenotype Ontology LOOM
http://purl.bioontology.org/ontology/MESH/D006111 Medical Subject Headings LOOM
http://purl.obolibrary.org/obo/DOID_12361 Human Disease Ontology 123 LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0018213 MedlinePlus Health Topics LOOM