National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Non-Hodgkin Lymphoma

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3211

ALT_DEFINITION

Any of a large group of cancers of lymphocytes (white blood cells). NHLs can occur at any age and are often marked by lymph nodes that are larger than normal, fever, and weight loss. There are many different types of NHL. These types can be divided into aggressive (fast-growing) and indolent (slow-growing) types, and they can be formed from either B-cells or T-cells. B-cell NHLs include Burkitt lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), diffuse large B-cell lymphoma, follicular lymphoma, immunoblastic large cell lymphoma, precursor B-lymphoblastic lymphoma, and mantle cell lymphoma. T-cell NHLs include mycosis fungoides, anaplastic large cell lymphoma, and precursor T-lymphoblastic lymphoma. Lymphomas that occur after bone marrow or stem cell transplantation are usually B-cell NHLs. Prognosis and treatment depend on the stage and type of disease.

A malignant neoplasm of the lymphatic system that is comprised of abnormal lymphocytes in the absence of Reed-Sternberg cells.

code

C3211

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103133

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102905

Contributing_Source

CTEP

CTRP

NICHD

MedDRA

DEFINITION

Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage.

Display_Name

Non-Hodgkin Lymphoma

FULL_SYN

Non-Hodgkin's Lymphoma (NHL)

Non-Hodgkin lymphoma, NOS

Non-Hodgkin's Lymphoma

NHL, NOS

NHL

Has_NICHD_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3208

ICD-O-3_Code

9591/3

label

Non-Hodgkin Lymphoma

Legacy_Concept_Name

Non-Hodgkin_s_Lymphoma

Neoplastic_Status

Malignant

NICHD_Hierarchy_Term

Non-Hodgkin Lymphoma

Preferred_Name

Non-Hodgkin Lymphoma

prefixIRI

C3211

prefLabel

Non-Hodgkin Lymphoma

Semantic_Type

Neoplastic Process

UMLS_CUI

C0024305

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3208

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7588

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/OMIM/MTHU014311 Online Mendelian Inheritance in Man LOOM
http://purl.obolibrary.org/obo/DOID_0060060 Cell Line Ontology Subset for Chinese National Infrastructure of Cell Line Resource (NICR) LOOM
http://purl.obolibrary.org/obo/DOID_0060060 Human Disease Ontology 123 LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0024305 MedlinePlus Health Topics LOOM