National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Multiple Sclerosis

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3243

ALT_DEFINITION

An autoimmune demyelinating disease characterized by a relapsing-remitting or progressive pattern of central nervous system impairment.

A disorder of the central nervous system marked by weakness, numbness, a loss of muscle coordination, and problems with vision, speech, and bladder control. Multiple sclerosis is thought to be an autoimmune disease in which the body's immune system destroys myelin. Myelin is a substance that contains both protein and fat (lipid), serving as a nerve insulator and helping in the transmission of nerve signals.

code

C3243

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

Contributing_Source

CTRP

NICHD

MedDRA

DEFINITION

A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers.

Display_Name

Multiple Sclerosis

Has_NICHD_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2934

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2889

label

Multiple Sclerosis

Legacy_Concept_Name

Multiple_Sclerosis

NICHD_Hierarchy_Term

Multiple Sclerosis

Preferred_Name

Multiple Sclerosis

prefixIRI

C3243

prefLabel

Multiple Sclerosis

Semantic_Type

Disease or Syndrome

UMLS_CUI

C0026769

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99383

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27586

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http://purl.bioontology.org/ontology/LNC/MTHU020805 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/LNC/LA14298-6 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/ICD10/G35 International Classification of Diseases, Version 10 LOOM
http://purl.bmicc.cn/ontology/ICD11CN/8A40 International Classification of Diseases, 11th Edition, China LOOM
http://purl.obolibrary.org/obo/DOID_2377 Human Disease Ontology 123 LOOM
http://purl.bioontology.org/ontology/MESH/D009103 Medical Subject Headings LOOM
http://purl.bioontology.org/ontology/ICD10CM/G35 International Classification of Diseases, Version 10 - Clinical Modification LOOM