Preferred Name |
Myelodysplastic Syndrome |
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3247 |
ALT_DEFINITION |
A group of diseases in which the bone marrow does not make enough healthy blood cells. A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow. A pre-malignant disorder characterized by blood cytopenias and abnormalities in bone marrow morphology. |
code |
C3247 |
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103128 |
Contributing_Source |
CTEP CTRP NICHD MedDRA |
DEFINITION |
A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) |
Display_Name |
Myelodysplastic Syndrome |
FULL_SYN |
MDS Dysmyelopoietic Syndrome Myelodysplastic Neoplasm Hematopoeitic - Myelodysplastic Syndrome (MDS) Preleukemia Myelodysplastic syndrome, NOS myelodysplastic syndromes Myelodysplastic Syndrome/Neoplasm Myelodysplasia Smoldering Leukemia Oligoblastic Leukemia |
Has_NICHD_Parent | |
ICD-O-3_Code |
9989/3 |
label |
Myelodysplastic Syndrome |
Legacy_Concept_Name |
Myelodysplastic_Syndrome |
Neoplastic_Status |
Undetermined |
NICHD_Hierarchy_Term |
Myelodysplastic Syndrome |
Preferred_Name |
Myelodysplastic Syndrome |
prefixIRI |
C3247 |
prefLabel |
Myelodysplastic Syndrome |
Semantic_Type |
Neoplastic Process |
UMLS_CUI |
C3463824 |
subClassOf |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54705 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9290 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27274 |