National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Myelodysplastic Syndrome

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3247

ALT_DEFINITION

A group of diseases in which the bone marrow does not make enough healthy blood cells.

A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow.

A pre-malignant disorder characterized by blood cytopenias and abnormalities in bone marrow morphology.

code

C3247

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103128

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102905

Contributing_Source

CTEP

CTRP

NICHD

MedDRA

DEFINITION

A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001)

Display_Name

Myelodysplastic Syndrome

FULL_SYN

MDS

Dysmyelopoietic Syndrome

Myelodysplastic Neoplasm

Hematopoeitic - Myelodysplastic Syndrome (MDS)

Preleukemia

Myelodysplastic syndrome, NOS

myelodysplastic syndromes

Myelodysplastic Syndrome/Neoplasm

Myelodysplasia

Smoldering Leukemia

Oligoblastic Leukemia

Has_NICHD_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3262

ICD-O-3_Code

9989/3

label

Myelodysplastic Syndrome

Legacy_Concept_Name

Myelodysplastic_Syndrome

Neoplastic_Status

Undetermined

NICHD_Hierarchy_Term

Myelodysplastic Syndrome

Preferred_Name

Myelodysplastic Syndrome

prefixIRI

C3247

prefLabel

Myelodysplastic Syndrome

Semantic_Type

Neoplastic Process

UMLS_CUI

C3463824

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54705

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9290

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27274

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7588

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C35501

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/OMIM/614286 Online Mendelian Inheritance in Man LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU024110 Online Mendelian Inheritance in Man LOOM
http://purl.obolibrary.org/obo/DOID_0050908 Human Disease Ontology 123 LOOM