Neurofibromatosis Type 1

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3273

A rare genetic condition that causes brown spots and tumors on the skin, freckling in skin areas not exposed to the sun, tumors on the nerves, and developmental changes in the nervous system, muscles, bone, and skin.

C3273

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

CTRP

The most common type of neurofibromatosis. It is characterized clinically by cutaneous and subcutaneous tumors with patches of hyperpigmentation. The hyperpigmented skin areas, are present from birth and found anywhere on the body surface. They can vary markedly in size and color. The dark brown areas are called cafe-au-lait spots. The multiple cutaneous and subcutaneous tumors are nerve sheath tumors, called neurofibromas. They can develop anywhere along the peripheral nerve fibers. Neurofibromas can become quite large, causing a major disfigurement, eroding bone, and compressing various peripheral nerve structures. Type 1 neurofibromatosis has dominant inheritance, with a gene locus on the proximal long arm of chromosome 17.

Neurofibromatosis Type 1

Von Recklinghausen Disease

NF1

Peripheral Neurofibromatosis

Neurofibromatosis 1

Neurofibromatosis Type 1

Neurofibromatosis_Type_1

Undetermined

Neurofibromatosis Type 1

C3273

Neurofibromatosis Type 1

Neoplastic Process

C0027831

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6727