Preferred Name |
Calcium Channel Blocker |
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C333 |
ALT_DEFINITION |
A pharmaceutical agent that inhibits the movement of calcium across through calcium channels in the cell membrane, preventing or decreasing the amount of calcium able to enter the cell. These drugs are used for their chronotropic, antihypertensive and vasodilatory effects. A class of drugs that act by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. Since they are inducers of vascular and other smooth muscle relaxation, they are used in the drug therapy of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms. |
CHEBI_ID |
CHEBI:38215 |
code |
C333 |
Concept_In_Subset | |
Contributing_Source |
NICHD |
DEFINITION |
A pharmaceutical agent that inhibits the movement of calcium across through calcium channels in the cell membrane, preventing or decreasing the amount of calcium able to enter the cell. These drugs are used for their chronotropic, antihypertensive and vasodilatory effects. |
FULL_SYN |
CCB |
Has_NICHD_Parent | |
label |
Calcium Channel Blocker |
Legacy_Concept_Name |
Calcium_Channel_Blocker |
NICHD_Hierarchy_Term |
Calcium Channel Blocker |
Preferred_Name |
Calcium Channel Blocker |
prefixIRI |
C333 |
prefLabel |
Calcium Channel Blocker |
Semantic_Type |
Chemical Viewed Functionally |
UMLS_CUI |
C0006684 |
subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://purl.obolibrary.org/obo/CHEBI_38215 | Chemical Entities of Biological Interest Ontology | LOOM |