loading...| Preferred Name |
Tuberculosis |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3423 |
| ALT_DEFINITION |
A disease caused by Mycobacterium tuberculosis infection that is characterized by the growth of nodules in body tissues, most commonly the lungs, and may be transmitted through droplets from the throat or lungs of individuals with the active respiratory disease. |
| code |
C3423 |
| Concept_In_Subset | |
| Contributing_Source |
NICHD MedDRA |
| DEFINITION |
A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use. |
| FULL_SYN |
TB |
| Has_NICHD_Parent | |
| label |
Tuberculosis |
| Legacy_Concept_Name |
Tuberculosis |
| NICHD_Hierarchy_Term |
Tuberculosis |
| Preferred_Name |
Tuberculosis |
| prefixIRI |
C3423 |
| prefLabel |
Tuberculosis |
| Semantic_Type |
Disease or Syndrome |
| UMLS_CUI |
C0041296 |
| subClassOf |