National Cancer Institute Thesaurus

Last uploaded: February 21, 2019

Preferred Name	Demyelinating Disorder
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34527
ALT_DEFINITION	Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.
code	C34527
Concept_In_Subset	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97150 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259
Contributing_Source	NICHD
DEFINITION	A broad group of disorders that affect the myelin sheaths that cover the neurons. Myelin sheathes cover neuronal axons in the central and peripheral nervous system and function to increase travelling impulse speeds. Disruption of this sheath impairs neuronal transmission and can result in disorders such as multiple sclerosis and Guillain-Barre syndrome, among others.
FULL_SYN	Demyelinating Disease
Has_NICHD_Parent	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26835
label	Demyelinating Disorder
Legacy_Concept_Name	Demyelinating_Disorder
NICHD_Hierarchy_Term	Demyelinating Disorder
Preferred_Name	Demyelinating Disorder
prefixIRI	C34527
prefLabel	Demyelinating Disorder
Semantic_Type	Disease or Syndrome
UMLS_CUI	C0011303
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4802

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