National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Monoclonal Gammopathy of Undetermined Significance

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3996

ALT_DEFINITION

A benign condition in which there is a higher-than-normal level of a protein called M protein in the blood. Patients with MGUS are at an increased risk of developing cancer.

code

C3996

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102905

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103130

Contributing_Source

CTEP

CTRP

DEFINITION

A plasma cell disorder in which an abnormal amount of a single immunoglobulin is present in the serum. Up to 25% of cases of monoclonal gammopathy of undetermined significance (MGUS) progress to a B-cell malignancy or myeloma. MGUS may occur in conjunction with various carcinomas, chronic inflammatory and infectious conditions, and other diseases.

Display_Name

Monoclonal Gammopathy of Undetermined Significance

FULL_SYN

MGUS

Benign Monoclonal Gammopathy

Monoclonal Gammopathy Of Undetermined Significance (MGUS)

Monoclonal Gammopathy of Unknown Significance

ICD-O-3_Code

9765/1

label

Monoclonal Gammopathy of Undetermined Significance

Legacy_Concept_Name

Monoclonal_Gammopathy_of_Undetermined_Significance

Neoplastic_Status

Malignant

Preferred_Name

Monoclonal Gammopathy of Undetermined Significance

prefixIRI

C3996

prefLabel

Monoclonal Gammopathy of Undetermined Significance

Semantic_Type

Neoplastic Process

UMLS_CUI

C0026470

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4665

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http://purl.bioontology.org/ontology/MESH/D008998 Medical Subject Headings LOOM