National Cancer Institute Thesaurus

Last uploaded: February 21, 2019

Preferred Name	Alkylation Process
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40468
code	C40468
DEFINITION	Alkylating Activity in biological systems is typically a process of covalent bonding in which a chemical substance replaces hydrogen atom(s) in biologically active molecules with alkyl radical(s), hindering proper function. DNA alkylation results in strand cross-linking and can inhibit DNA replication.
FULL_SYN	Alkylation
label	Alkylation Process
Legacy_Concept_Name	Alkylating_Activity
Preferred_Name	Alkylation Process
prefixIRI	C40468
prefLabel	Alkylation Process
Semantic_Type	Phenomenon or Process
UMLS_CUI	C0002074
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19899

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