loading...| Preferred Name |
Renal Failure |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4376 |
| ALT_DEFINITION |
An acute or chronic condition that is characterized by the inability of the kidneys to adequately filter the blood. A condition in which the kidneys stop working and are not able to remove waste and extra water from the blood or keep body chemicals in balance. Acute or severe renal failure happens suddenly (for example, after an injury) and may be treated and cured. Chronic renal failure develops over many years, may be caused by conditions like high blood pressure or diabetes, and cannot be cured. Chronic renal failure may lead to total and long-lasting renal failure, called end-stage renal disease (ESRD). A person in ESRD needs dialysis (the process of cleaning the blood by passing it through a membrane or filter) or a kidney transplant. The inability of a kidney to excrete metabolites at normal plasma levels under conditions of normal loading, or the inability to retain electrolytes under conditions of normal intake. In the acute form (KIDNEY FAILURE, ACUTE), it is marked by uremia and usually by oliguria or anuria, with hyperkalemia and pulmonary edema. The chronic form (KIDNEY FAILURE, CHRONIC) is irreversible and requires hemodialysis. |
| code |
C4376 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123272 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 |
| Contributing_Source |
CTRP NICHD MedDRA FDA |
| DEFINITION |
An acute or chronic condition that is characterized by the inability of the kidneys to adequately filter the blood. |
| Display_Name |
Renal Failure |
| FDA_Table |
Patient Code (Appendix B) |
| FULL_SYN |
Renal Failure Syndrome Kidney Failure Renal Insufficiency Failure, Renal |
| Has_CDRH_Parent | |
| Has_NICHD_Parent | |
| label |
Renal Failure |
| Legacy_Concept_Name |
Renal_Failure |
| NICHD_Hierarchy_Term |
Renal Failure |
| Preferred_Name |
Renal Failure |
| prefixIRI |
C4376 |
| prefLabel |
Renal Failure |
| Semantic_Type |
Disease or Syndrome |
| UMLS_CUI |
C0035078 |
| subClassOf |