National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Optic Nerve Glioma

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4537

ALT_DEFINITION

Glial cell derived tumors arising from the optic nerve, usually presenting in childhood. Roughly 50% are associated with NEUROFIBROMATOSIS 1. Clinical manifestations include decreased visual acuity; EXOPHTHALMOS; NYSTAGMUS; STRABISMUS; pallor or swelling of the optic disc; and INTRACRANIAL HYPERTENSION. The tumor may extend into the optic chiasm and hypothalamus. (Adams et al., Principles of Neurology, 6th ed, p681)

code

C4537

DEFINITION

A glioma that affects the optic nerve. This condition can be seen in association with neurofibromatosis 1. It is most commonly seen in the pediatric age group.

FULL_SYN

Glioma of Optic Nerve

Glioma of the Optic Nerve

label

Optic Nerve Glioma

Legacy_Concept_Name

Optic_Nerve_Glioma

Neoplastic_Status

Undetermined

Preferred_Name

Optic Nerve Glioma

prefixIRI

C4537

prefLabel

Optic Nerve Glioma

Semantic_Type

Neoplastic Process

UMLS_CUI

C0346326

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4801

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8567

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http://purl.obolibrary.org/obo/HP_0009734 Human Phenotype Ontology LOOM
http://purl.bioontology.org/ontology/MESH/D020339 Medical Subject Headings LOOM
http://purl.obolibrary.org/obo/DOID_4992 Human Disease Ontology 123 LOOM