National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Alpha-Methylacyl-CoA Racemase

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48211

code

C48211

DEFINITION

Alpha-methylacyl-CoA racemase (382 aa, ~42 kDa) is encoded by the human AMACR gene. This protein plays a role in the beta-oxidation of branched-chain fatty acids.

DesignNote

Overexpression of alpha-methylacyl-CoA racemase has been found in several carcinomas, thus it is considered an important biomarker in the pathogenesis of breast, prostate, and colon cancers.

FULL_SYN

EC 5.1.99.4

2-methylacyl-CoA Racemase

AMACR

X-methylacyl-CoA Racemase

label

Alpha-Methylacyl-CoA Racemase

Legacy_Concept_Name

Alpha-methylacyl-CoA_Racemase

OMIM_Number

604489

Preferred_Name

Alpha-Methylacyl-CoA Racemase

prefixIRI

C48211

prefLabel

Alpha-Methylacyl-CoA Racemase

Semantic_Type

Enzyme

Amino Acid, Peptide, or Protein

Swiss_Prot

Q9UHK6

UMLS_CUI

C0666209

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16759

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http://purl.bioontology.org/ontology/OMIM/604489 Online Mendelian Inheritance in Man LOOM
http://purl.bioontology.org/ontology/LNC/MTHU054498 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/LNC/LP201758-2 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/MESH/C108352 Medical Subject Headings LOOM
http://purl.obolibrary.org/obo/PR_000003984 Protein Ontology LOOM