loading...| Preferred Name |
Free Radical |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C512 |
| ALT_DEFINITION |
A type of unstable molecule that is made during normal cell metabolism (chemical changes that take place in a cell). Free radicals can build up in cells and cause damage to other molecules, such as DNA, lipids, and proteins. This damage may increase the risk of cancer and other diseases. |
| CHEBI_ID |
CHEBI:26519 |
| code |
C512 |
| DEFINITION |
Molecules or atoms with at least one unpaired or 'free' electron in the outermost electron shell. Chemically unstable, free radicals stabilize themselves by appropriating an electron from a nearby molecule, thereby damaging that molecule by altering the electron number in its outermost electron shell. By-products of both normal cell processes and environmental toxin exposure, oxygen free-radicals in high concentrations may damage DNA, proteins, and lipids, thereby increasing the risk for various diseases including cancer. (NCI04) |
| FULL_SYN |
Free Radicals |
| label |
Free Radical |
| Legacy_Concept_Name |
Free_Radicals |
| Preferred_Name |
Free Radical |
| prefixIRI |
C512 |
| prefLabel |
Free Radical |
| Semantic_Type |
Inorganic Chemical |
| UMLS_CUI |
C0016693 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||