National Cancer Institute Thesaurus

Last uploaded: February 21, 2019

Preferred Name	IRX-2
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C53396
code	C53396
DEFINITION	A cell-free mixture comprised of a variety of naturally-derived cytokines obtained from normal, unrelated donor lymphocytes with potential immunostimulatory activity. The cytokines in IRX-2, including interleukin (IL)-1, -2, -6, -8, -10, -12, tumor necrosis factor alpha (TNF-a), interferon-gamma (IFN-g) and colony stimulating factors (CSFs), play vital roles in regulating cellular immunity and may synergistically stimulate a cellular immune response against tumor cells.
label	IRX-2
Legacy_Concept_Name	IRX-2
PDQ_Closed_Trial_Search_ID	462160
PDQ_Open_Trial_Search_ID	462160
Preferred_Name	IRX-2
prefixIRI	C53396
prefLabel	IRX-2
Semantic_Type	Pharmacologic Substance Amino Acid, Peptide, or Protein
UMLS_CUI	C0758290
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1283

Delete	Subject	Author	Type	Created
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Delete	Mapping To	Ontology	Source
	http://purl.obolibrary.org/obo/OGG_3000153572	Ontology of Genes and Genomes	LOOM
	http://purl.bioontology.org/ontology/MESH/C114857	Medical Subject Headings	LOOM