loading...| Preferred Name |
Methadone |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62044 |
| CAS_Registry |
76-99-3 |
| CHEBI_ID |
CHEBI:6807 |
| Chemical_Formula |
C21H27NO |
| code |
C62044 |
| Concept_In_Subset | |
| Contributing_Source |
FDA |
| DEFINITION |
A synthetic opioid with analgesic activity. Methadone mimics the actions of endogenous peptides at CNS opioid receptors, primarily on the mu-receptor and has actions similar to those of morphine and morphine-like agents. The characteristic morphine-like effects include analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia and physical dependence. However, the detoxification symptoms between morphine-like agents and methadone differ in that the onset of methadone's withdrawal symptoms is slower, the course is more prolonged and the symptoms are less severe. |
| FDA_UNII_Code |
UC6VBE7V1Z |
| Has_Salt_Form | |
| label |
Methadone |
| Legacy_Concept_Name |
Methadone_Base |
| Preferred_Name |
Methadone |
| prefixIRI |
C62044 |
| prefLabel |
Methadone |
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
| UMLS_CUI |
C0025605 |
| subClassOf |