National Cancer Institute Thesaurus

Last uploaded: February 21, 2019

Preferred Name	Cefmetazole
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65297
CAS_Registry	56796-20-4
CHEBI_ID	CHEBI:3489
Chemical_Formula	C15H17N7O5S3
code	C65297
Concept_In_Subset	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923
Contributing_Source	FDA
DEFINITION	A second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefmetazole binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.
FDA_UNII_Code	3J962UJT8H
Has_Salt_Form	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65298
label	Cefmetazole
Legacy_Concept_Name	Cefmetazole
Preferred_Name	Cefmetazole
prefixIRI	C65297
prefLabel	Cefmetazole
Semantic_Type	Pharmacologic Substance
UMLS_CUI	C0007550
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C357

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/LNC/LP17800-1	Logical Observation Identifier Names and Codes	LOOM
http://purl.bioontology.org/ontology/MESH/D015311	Medical Subject Headings	LOOM
http://purl.obolibrary.org/obo/CHEBI_3489	Chemical Entities of Biological Interest Ontology	LOOM
http://purl.obolibrary.org/obo/CHEBI_3489	GenEpiO	LOOM
http://purl.bmicc.cn/ontology/ICD11CN/XM8S59	International Classification of Diseases, 11th Edition, China	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU001884	Logical Observation Identifier Names and Codes	LOOM