National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Myeloperoxidase

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C71145

code

C71145

DEFINITION

Myeloperoxidase (745 aa, ~84 kDa) is encoded by the human MPO gene. This protein is involved in the regulation of the innate host defense through the production of hypohalous acids.

DesignNote

Myeloperoxidase is synthesized as a single chain precursor that is cleaved into a light and heavy chain. The mature enzyme is a tetramer composed of 2 light chains and 2 heavy chains. (EntrezGene)

FULL_SYN

EC 1.11.1.7

MPO

label

Myeloperoxidase

Legacy_Concept_Name

Myeloperoxidase

OMIM_Number

606989

Preferred_Name

Myeloperoxidase

prefixIRI

C71145

prefLabel

Myeloperoxidase

Semantic_Type

Enzyme

Amino Acid, Peptide, or Protein

Swiss_Prot

P05164

UMLS_CUI

C0027021

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16946

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http://purl.bioontology.org/ontology/LNC/MTHU022358 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/LNC/LP29281-0 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/OMIM/606989 Online Mendelian Inheritance in Man LOOM
http://purl.obolibrary.org/obo/PR_000010543 Phenotypic Quality Ontology LOOM
http://purl.obolibrary.org/obo/PR_000010543 Cell Ontology LOOM
http://purl.obolibrary.org/obo/PR_000010543 Protein Ontology LOOM
http://purl.obolibrary.org/obo/PR_000010543 Cell Line Ontology Subset for Chinese National Infrastructure of Cell Line Resource (NICR) LOOM