National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Localized Scleroderma

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C72069

ALT_DEFINITION

An autoimmune disorder marked by excessive production of collagen resulting in hardening and thickening of skin, with formation of patches or lines of thick and unyielding tissue. There can also be musculoskeletal and underlying tissue involvement. The affected areas of skin can be restrictive and disfiguring.

code

C72069

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118468

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

Contributing_Source

CTRP

NICHD

MedDRA

DEFINITION

A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. Localized scleroderma typically affects the skin, with formation of patches or lines of thick and unyielding tissue; there can be muscle and underlying tissue involvement as well as occasional joint complications. The affected areas of skin can be restrictive and disfiguring. The shape, depth and location of the affected area is used to classify one of the four types of local scleroderma. An individual can have a combination of localized scleroderma types.

Display_Name

Localized Scleroderma

FULL_SYN

Morphea

Has_NICHD_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26746

label

Localized Scleroderma

Legacy_Concept_Name

Localized_Scleroderma

NICHD_Hierarchy_Term

Localized Scleroderma

Preferred_Name

Localized Scleroderma

prefixIRI

C72069

prefLabel

Localized Scleroderma

Semantic_Type

Disease or Syndrome

UMLS_CUI

C0036420

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26746

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http://purl.obolibrary.org/obo/DOID_8472 Human Disease Ontology 123 LOOM