National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Polycyclic Aromatic Hydrocarbons

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C761

ALT_DEFINITION

A major group of unsaturated cyclic hydrocarbons containing two or more rings. The vast number of compounds of this important group, derived chiefly from petroleum and coal tar, are rather highly reactive and chemically versatile. The name is due to the strong and not unpleasant odor characteristic of most substances of this nature. (From Hawley's Condensed Chemical Dictionary, 12th ed, p96)

CHEBI_ID

CHEBI:33848

code

C761

DEFINITION

Polycyclic aromatic hydrocarbons (PAH) are a large class of organic compounds containing two or more fused aromatic rings made up of carbon and hydrogen atoms. They have high melting and boiling-points, low vapour pressure, water solubility, and are highly lipophilic. PAH are produced during incomplete combustion or pyrolysis of organic matter, are found in cigarette smoke, motor vehicle exhaust, used motor lubricating oil, broiled meat, coal tar, crude oil, creosote, roofing tar, dyes, plastics, and pesticides. Some members of PAH class were shown to have carcinogenic, genotoxic, and immunotoxic properties, developmental toxicity and affect reproductive health. (NCI)

label

Polycyclic Aromatic Hydrocarbons

Legacy_Concept_Name

Polycyclic_Aromatic_Hydrocarbons

Preferred_Name

Polycyclic Aromatic Hydrocarbons

prefixIRI

C761

prefLabel

Polycyclic Aromatic Hydrocarbons

Semantic_Type

Organic Chemical

Chemical Viewed Structurally

UMLS_CUI

C0032458

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C553

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