loading...| Preferred Name |
Prednisone |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C770 |
| Accepted_Therapeutic_Use_For |
Inflammatory conditions; Allergic conditions; Hematologic conditions; Neoplastic conditions; Autoimmune conditions; Replacement therapy in adrenal insufficiency |
| ALT_DEFINITION |
A drug used to lessen inflammation and lower the body's immune response. It is used with other drugs to treat leukemia and lymphoma and other types of cancer. It is also used alone or with other drugs to prevent or treat many other conditions. These include conditions related to cancer, such as anemia (a low level of red blood cells), allergic reactions, and loss of appetite. Prednisone is a type of therapeutic glucocorticoid. |
| CAS_Registry |
53-03-2 |
| CHEBI_ID |
CHEBI:8382 |
| Chemical_Formula |
C21H26O5 |
| code |
C770 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP FDA |
| DEFINITION |
A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations. |
| Display_Name |
Prednisone |
| FDA_UNII_Code |
VB0R961HZT |
| FULL_SYN |
.delta.1-Cortisone Predicorten Prednitone 1,2-Dehydrocortisone Delta-Dome Deltasone Delta 1-Cortisone SK-Prednisone Decortisyl Prednisonum Cortancyl Econosone Promifen 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione Prednicort Deltadehydrocortisone Adasone Meticorten Predniment Deltacortisone Deltison Ofisolona Lisacort Liquid Pred Orasone Paracort Prednidib DeCortin Deltacortene Servisone Prednicen-M Predeltin Panafcort Dacortin Meprosona-F Panasol-S PRED Deltra Decorton Metacortandracin Predicor 1, 2-Dehydrocortisone Prednilonga Sterapred |
| label |
Prednisone |
| Legacy_Concept_Name |
Prednisone |
| NSC_Code |
10023 |
| PDQ_Closed_Trial_Search_ID |
42487 |
| PDQ_Open_Trial_Search_ID |
42487 |
| Preferred_Name |
Prednisone |
| prefixIRI |
C770 |
| prefLabel |
Prednisone |
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
| UMLS_CUI |
C0032952 |
| subClassOf |