National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Protease Inhibitor

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C783

ALT_DEFINITION

A compound that interferes with the ability of certain enzymes to break down proteins. Some protease inhibitors can keep a virus from making copies of itself (for example, AIDS virus protease inhibitors), and some can prevent cancer cells from spreading.

CHEBI_ID

CHEBI:37670

code

C783

DEFINITION

Any substance that inhibits a protease, an enzyme that breaks peptide bonds. Proteases are required for many cell processes and inhibition of proteases can inhibit viral replication, inflammatory responses, proliferation, and tumor growth.

FULL_SYN

Protease Inhibitors

label

Protease Inhibitor

Legacy_Concept_Name

Protease_Inhibitor

Preferred_Name

Protease Inhibitor

prefixIRI

C783

prefLabel

Protease Inhibitor

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C0033607

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C471

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http://purl.obolibrary.org/obo/CHEBI_37670 Chemical Entities of Biological Interest Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 International Classification of Diseases Ontology LOOM