National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
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Preferred Name

Quinolone Antibiotic
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C795
ALT_DEFINITION

A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID.
code

C795
DEFINITION

The basic structure of quinolone is nalidixic acid that has limited therapeutic value. However, the development of fluorinated quinolones led to new derivative compounds with broad antibacterial activity. Both DNA gyrase and topoisomerase IV are targets of quinolones.
label

Quinolone Antibiotic
Legacy_Concept_Name

Quinolone_Antibiotic
Preferred_Name

Quinolone Antibiotic
prefixIRI

C795
prefLabel

Quinolone Antibiotic
Semantic_Type

Chemical Viewed Functionally
UMLS_CUI

C1882518
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C258
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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_86324 Chemical Entities of Biological Interest Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 GenEpiO LOOM